BME Spring Seminar: A Tale of Two Biopolymers: Imaging the Nanoporosity of Mucus and Collagen with Diffusion-Sensitive Optical Coherence Tomography - College of Engineering - University of Wisconsin-Madison BME Spring Seminar: A Tale of Two Biopolymers: Imaging the Nanoporosity of Mucus and Collagen with Diffusion-Sensitive Optical Coherence Tomography - College of Engineering - University of Wisconsin-Madison

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BME Spring Seminar: A Tale of Two Biopolymers: Imaging the Nanoporosity of Mucus and Collagen with Diffusion-Sensitive Optical Coherence Tomography

March 5 @ 12:00 pm - 1:00 pm

Presented by

Amy Oldenburg, Ph.D.; Assoc. Professor, UNC Chapel Hill


From the mucus that lines our airways, to the collagen that comprises our soft tissues, much of the human body can be thought of as a biopolymeric mesh filled with water. Remodeling of the mesh structure occurs in many, if not most, disease processes.

This talk will discuss the development and application of a new method, diffusion-sensitive optical coherence tomography (DS-OCT), which employs plasmonic nanoparticles capable of penetrating the biological pore structure and reporting the local nanopore size based upon changes in their stochastic diffusion. Interestingly, DS-OCT enables the inference of nano-scale information about biological samples using an imaging modality (OCT) of much coarser (micro-scale) resolution, with high speed and only minimal invasiveness. Applications in lung disease and breast cancer will be presented.

 

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Date:

March 5

Time:

12:00 pm - 1:00 pm

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Organizer

Department of Biomedical Engineering
Phone:
608-263-4660
Email:
bmehelp@bme.wisc.edu
Website:
https://www.engr.wisc.edu/department/bme/

Venue

Room 1003 (Tong Auditorium) Engineering Centers Building
1550 Engineering Drive
Madison, WI 53706 United States
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