BME Seminar Series: Melissa Kinney - College of Engineering - University of Wisconsin-Madison BME Seminar Series: Melissa Kinney - College of Engineering - University of Wisconsin-Madison

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BME Seminar Series: Melissa Kinney

November 14 @ 12:30 pm - 1:30 pm

Toward a Systems-Level Understanding of Stem Cell Fate

Abstract (PDF)

Stem cell-derived organoids promise broad translational potential for applications ranging from drug screening to transplantation and regeneration. These complex, and often functional, tissue-like structures arise largely from endogenous patterning and morphogenesis of pluripotent stem cells within three-dimensional spheroids.

Our research efforts aim to control and perturb these processes through a quantitative understanding of stem cell fate dynamics and engineering of the biophysical spheroid microenvironment. This seminar will present insights into the integration of extrinsic stimuli, cell intrinsic cues and signaling mechanisms, raising questions on how to establish design parameters and judiciously perturb these complex stem cell systems.

Date:

November 14

Time:

12:30 pm - 1:30 pm

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Venue

1153 Mechanical Engineering
1513 University Ave
Madison, WI 53706 United States
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