Chemical and Engineering News: Keeping bacterial infections at bay using peptide-containing nanofibers

// Chemical & Biological Engineering

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This article in Chemical and Engineering News features research by David Lynn, Duane H. and Dorothy M. Bluemke Professor and Vilas Distinguished Achievement Professor in chemical and biological engineering.

Forced into a literal do-or-die situation, bacteria evolve ways to evade death from antibiotics. These adaptations eventually lead to the problem of antibiotic resistance. One way to sidestep this problem could be to take the pressure off bacteria and let them live, while also blocking their ability to cause harmful infection. Using this approach, researchers have developed a new material made of nanofibers with peptides incorporated that block infection without killing bacterial cells. The easy-to-make material could be integrated into dressings for wounds, the researchers say (ACS Infect. Dis. 2017, DOI: 10.1021/acsinfecdis.6b00173). More…