Ray Vanderby, Jr. Professor Address/E-mail Program Affiliations Courses Education Fields of Interest Publications Additional Experience Summary

Contact Information

Module G5/360 Clinical Science Center 600 Highland Avenue Madison, WI 53792

Tel: 608/263-9593 Fax: 608/265-9144 E-mail: vanderby@orthorehab.wisc.edu

Program Affiliations

• Biomedical Engineering
• Engineering Physics
• Mechanical Engineering

• Biomedical Engineering Center
• Engineering Mechanics
• Materials Science Program
• Orthopedics and Rehabilitation

Courses

• BME 615: Tissue Mechanics

Education

• BS, 1968, Purdue University
• MS, 1972, Purdue University
• PhD, 1975, Purdue University
• Post Doctoral Fellow, University of Connecticut

Fields of Interest

• tissue mechanics (bone, ligament, tendon, and cartilage)
• tissue engineering
• connective tissue healing
• orthopedic biomechanics

Publications

• Provenzano P, Lakes R, Keenan T, Vanderby R. Non-linear ligament viscoelasticity. Ann Biomed Eng. 2001; 29(10): 908-914.
• Provenzano P, Heisey D, Hayashi K, Lakes R, Vanderby R. Sub-failure damage in ligament: A structural and cellular evaluation. J Appl Physiol. 2002; 92(1): 362-371.
• Provenzano PP, Lakes RS, Corr DT, Vanderby R. Application of nonlinear viscoelastic models to describe ligament behavior. Biomech Modeling Mechanobiology. 2002; 1(1): 45-57.
• Provenzano PP, Hayashi K, Kunz DN, Markel MD, Vanderby R. Healing of subfailure ligament injury: comparison between immature and mature ligaments in a rat model. J Orthop Res. 2002; 20(5):975-83.
• Provenzano PP, Martinez DA, Grindeland RE, Dwyer KW, Turner J, Vailas AC, Vanderby R. Hindlimb unloading alters ligament healing. J Appl Physiol. 2003;94(1):314-24.
• Oza, A., Vanderby R., Lakes RS. Interrelation of creep and relaxation for nonlinearly viscoelastic materials: application to ligament and metal. Rheologica Acta. 2003; 42: 557-568.
• Hurschler C, Provenzano PP, Vanderby R. Scanning electron microscopic characterization of healing and normal rat ligament microstructure fixed under slack and loaded conditions. Conn Tissue Res. 2003; 44(2): 59-68.
• Provenzano P, Martinez D, Grindeland R, Dwyer K, Turner J, Vailas A, Vanderby R. Hindlimb unloading alters healing in medial collateral ligament. J Appl Phys. 2003; 94: 313-324.
• Hurschler C, Provenzano P, Vanderby R. Application of a Probablilistic Microstructural Model to Determine Reference Length and Toe-to-Linear Region Transition in Fibrous Connective Tissue. J Biomech Eng. 2003; 125(3): 415-422.
• Danova N, Colopy S, Kalscheur V, Markel M, Vanderby R, McCabe R, Escarcega A, Muir P. Degradation of bone structural properties by accumulation and coalescence of microcracks. Bone. 2003; 33: 197-205.
• Dwyer KW Provenzano PP, Muir P, Valhmu WB, Vanderby R Jr. Blockade of the sympathetic nervous system degrades ligament in a rat MCL model. J Appl Physiol. 2004 96(2):711-8.
• Hingorani RV, Provenzano PP, Lakes RS, Escarcega A, Vanderby R, Jr. Nonlinear viscoelasticity in rabbit medial collateral ligament. Ann Biomed Eng 2004; 32:306-312.
• Kobayashi H, Vanderby R. A new strain energy function for acoustoelastic analysis of dilatational waves in nearly incompressible, hyper-elastic materials. J Appl Mech. 2005; 72(6): 843-851.
• Provenzano P, Alejandro-Osorio A, Valhmu W, Jensen K, Vanderby R. Intrinsic fibroblast mediated remodeling of damaged collagenous matrices in vivo. Matrix Biol. 2005, 23: 543-555.

Additional Experience

• McDonnell Douglas Corporation
• Union Carbide Corporation
• Illinois Institute of Technology
• Northwestern University

Summary

Dr. Vanderby is a professor in the Biomedical Engineering Department and in the Orthopedics and Rehabilitation Department where he directs the Orthopedic Research Laboratories. He has an affiliate appointment in the Departments of Engineering Physics and Mechanical Engineering. His research focuses entirely on orthopedic issues.

Vanderby is particularly interested in orthopedic tissues (bone, ligament, tendon, cartilage, etc.). His research focuses on wound healing or regeneration of these tissues via tissue engineering. This includes equal parts of functional characterization (e.g. biomechanics), microstructural morphology and composition, and the relevant biological sciences (cell and molecular biology, histology, etc.).

Additionally, Vanderby is interested in ultrasonic wave propagation in these tissues for clinically relevant characterization, in knee reconstruction, in fracture fixation, and in the biomechanics of the spine. To study these orthopedic issues, he uses and adapts engineering and biological methods including experimental, analytical, and computational mechanics.