Kristyn S. Masters Assistant Professor Address/E-mail Program Affiliations Courses Education Fields of Interest Selected Publications Summary For additional information, see my

Contact Information

2152 Engineering Centers Building 1550 Engineering Drive Madison, WI 53706

Tel: 608/265-4052 Fax: 608/265-9239 E-mail: kmasters@wisc.edu

Program Affiliations

• Biomedical Engineering

• Biomedical Engineering Center for Translational Research
• Materials Science Program

Courses

• BME 200: Biomedical Engineering Design
• BME 201: Biomedical Engineering Design
• BME 300: Biomedical Engineering Design
• BME 301: Biomedical Engineering Design
• BME 510: Introduction to Tissue Engineering

Education

• Postdoctoral research 2001-2003, Chemical Engineering, University of Colorado-Boulder
• Ph.D. 2001, Chemical Engineering, Rice University
• B.S. 1997, Chemical Engineering, University of Michigan-Ann Arbor

Fields of Interest

• Synthesis of bioactive materials that direct cell function
• Characterization of cell-material interactions
• Tissue Engineering
• Drug Delivery

Selected Publications

• Stefonek TJ, Masters KS. Immobilized Gradients of Epidermal Growth Factor Promote Accelerated and Directed Keratinocyte Migration. Wound Repair Regen, In press.
• Sebra RP, Reddy SK, Masters KS, Bowman CN, Anseth KS. Using Controlled Polymerization Chemistry to Graft Architectures that Influence Cell-Material Interactions Acta Biomaterialia, 2007; 3:151-61.
• Sebra RP, Masters KS, Bowman CN, Anseth KS. Rapid antigen detection in a biologically complex fluid using photografted whole antibodies. Anal Chem, 2006; 78: 3144-3151.
• Sebra RP, Masters KS, Bowman CN, Anseth KS. Surface Grafted Antibodies: Controlled Architecture Permits Enhanced Antigen Detection. Langmuir 2005; 21: 10907-10911.
• Masters KS, Murphy WL. Tissue Engineering. In: Webster JG, editor. Encyclopedia of Medical Devices and Instrumentation, 2nd edition, Volume 6. Wiley-Interscience Publishers, 2006.
• Cushing MC, Jaeggli MP, Masters KS, Leinwand LA, Anseth KS. Serum deprivation improves seeding and repopulation of acellular matrices with valvular interstitial cells. J Biomed Mater Res 2005; 75A: 232-241.
• Masters KS, Lipke EA, Rice EEH, Liel MS, Myler HA, Zygourakis C, Tulis DA, West JL. Nitric oxide-generating hydrogels inhibit neointima formation. J Biomater Sci Polym Edn, 2005; 16: 659-672.
• Masters KS, Shah DN, Anseth KS. Crosslinked hyaluronan scaffolds as a biologically active carrier for valvular interstitial cells. Biomaterials 2005; 26: 2517-2525.
• Masters KS, Shah DN, Anseth KS. Designing Scaffolds for Valvular Interstitial Cells: Cell Adhesion and Function on Naturally-Derived Materials. J Biomed Mater Res 2004; 71A: 172-180.
• Masters KS, Mann BK. Tissue Engineered Heart. In: Nedovic V, Willaert R, editors. Cell Immobilisation Biotechnology. New York, NY Kluwer Academic Publishers, In Press.
• Walker G, Masters KS, Shah DN, Anseth KS, Leinwand LA. Valvular myofibroblast activation by TGF-beta: Implications for pathological ECM remodeling in heart valve disease. Circ Res 2004; 95: 261-268.
• Masters KS, Anseth KS. Cell-Material Interactions. In: Peppas NA, Sefton MV, editors. Molecular and Cellular Foundations of Biomaterials. Advances in Chemical Engineering, Vol. 29. Academic Press, 2004.
• Bohl-Masters KS, Leibovich SJ, Belem P, West JL, Poole-Warren LA. The effects of nitric oxide releasing poly(vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice. Wound Rep Regen 2002; 10: 286-294.
• Bohl-Masters KS, West JL. Pharmacologically active biomaterials. In: Dillow AK, Lowman AM, editors. Biomimetic Materials and Design: Interactive Biointerfacial Strategies, Tissue Engineering and Targeted Drug Delivery. New York, NY: Marcel Dekker, Inc., 2002.
• Schmedlen RH, Masters KS, West JL. Photocrosslinkable polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering. Biomaterials 2002; 23: 4325-4332.
• Tulis DA, Bohl-Masters KS, Lipke EA, Schiesser RL, Evans AJ, Peyton KJ, Durante W, West JL, Schafer AI. YC-1-mediated vascular protection through inhibition of smooth muscle cell proliferation and platelet function. Biochem Biophys Res Comm 2002; 291: 1014-1021.
• Bohl KS, West J. Nitric oxide-generating polymers reduce platelet adhesion and smooth muscle cell proliferation. Biomaterials, 2000; 21 (22): 2273-78.

Summary

By combining engineering and biological principles, my lab investigates fundamental issues in cell-material interactions in order to create 'smarter', bioactive materials that are capable of directing cell function. The projects in my lab entail research in a wide variety of fields, including materials design, drug delivery, and physiological characterization with the end goal of creating unique biomaterial systems with clinical applicability.

Copyright 2007 The Board of Regents of the University of Wisconsin System Date last modified: 12-Jun-2007 Content by: kmasters@wisc.edu Accessibility Web services Thank you for visiting http://www.engr.wisc.edu/bme/faculty/masters_kristyn.html UPDATE PROFILE