Gong, Shaoqin "Sarah"

Biomaterials (e.g., drug delivery, tissue engineering scaffolds), biosensors, functional polymer nanocomposites (e.g., actuators, sensors), biobased plastics, and microcellular plastics.
Prof. Gong's lab currently has openings for graduate students/postdocs/visiting scholars with a strong background in polymer chemistry and materials science. Researchers with expertise in developing novel biomaterials and biodevices or functional polymer nanocomposites are strongly encouraged to apply via email.

Publications

Selected publications in 2008, 2009, 2010, 2011:

Xiao, Y., Hao, H., Javadi, A., Englec. J., Xu, W., Yang, Y., Zhang, Y., Barnhart, T., Cai, W. and Gong, S., Multifunctional Unimolecular Micelles for Cancer-targeted Drug Delivery and Positron Emission Tomography Imaging, Biomaterials, in press, 2012. (Leading Opinion Paper)
Javadi, A., Xiao, Y., Xu, W., and Gong, S., Chemically Modified Graphene/P(VDF-TrFE-CFE) Electeroactive Polymer Nanocomposites with Superior Electromechanical Performance, Journal of Materials Chemistry, DOI: 10.1039/C1JM13786G
Yang, X. Hong, H., Grailer J.J., Rowland, I.J., Javadi, A., Hurley, S.A., Xiao, Y., Yang, Y., Zhang, Y., Nickles, R. J., Cai, W., Steeber, D.A., Gong, S., cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging, Biomaterials, 32 (17), 4151-60 (2011).
Yang, X., Grailer, J. J., Rowland, I. J., Javadi, A., Hurley, S.A., Vyara, M., Steeber, D. A., and Gong, S., Multifunctional Stable and pH-Responsive Polymer Vesicles Formed by Heterofunctional Triblock Copolymer for Targeted Anti-Cancer Drug Delivery and Ultrasensitive MR Imaging, ACS Nano, 4 (11), pp.6805-6817(2010).
Yang, M., Javadi, A., and Gong, S., Sensitive Electrochemical Immunosensor for the Detection of Cancer Biomarker Using Quantum Dot Functionalized Graphene Sheets as Labels, Sensors & Actuators: B. Chemical, 155 (1), 357-360 (2011).
Javadi, A., Srithep Y., Pilla, S., Clemons, C., Gong, S., and Turng, L. S., Microcellular Poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV)-Hyperbranched Polymer-Nanoclay Nanocomposites, Polymer Science and Engineering, 51 (9), 1815-1826 (2011).
Yang, X., Grailer, J. J., Rowland, I. J., Javadi, A., Hurley, S.A., Steeber, D. A., and Gong, S., Multifunctional SPIO/DOX-loaded Wormlike Polymer Vesicles for Cancer Therapy and MR Imaging, Biomaterials,31(34), pp.9065-73(2010).
Srithep Y., Javadi, A., Pilla, S., Lee, J., Clemons, C., Gong, S., and Turng, L. S., Jun, P., Processing and Characterization of Recycled Poly(ethylene terephthalate) (PET) Blends with Chain Extenders (CE), Thermoplastic Elastomer (TPE), and/or Poly(butylene adipate-co-terephthalate) (PBAT), Polymer Engineering and Science, in press, 2010.
Yang, M., Javadi, A., Li, H. and Gong, S., Ultrasensitive Immunosensor for the Detection of Cancer Biomarker Based on Graphene Sheet, Biosensors and Bioelectronics, 26 (2), 560-565 (2010).
Pilla, S., Kramschuster, A., Lee, J., Clemons, C., Gong, S., and Turng L.-S., Microcellular Processing of Polylactide-Hyperbranched Polyester-Nanoclay Nanocomposties, Journal of Materials Science, 45(10), pp. 2732-2746 (2010).
Yang, X., Grailer, J. J., Pilla, S., Steeber, D. A., Gong, S., Shuai, X., 2010, Multifunctional Polymeric Vesicles for Targeted Drug Delivery and Imaging, Biofabrication 2 (2010) 025004 (8pp).
Yang, M. and Gong, S., Immunosensor for the Detection of Cancer Biomarker based on Percolated Graphene Thin Film, Chemical Communications, 46, 5796-5798 (2010). (Top five accessed articles of the month)
Javadi, A., Srithep Y., Pilla, S., Lee, J., Clemons, C., Gong, S., and Turng, L. S., Processing and Characterization of Microcellular PHBV/PBAT blends and its Recycled Wood Fiber/Nanoclay Composites, Composite Part A-Applied Science and Manufacturing, 41 (8), pp. 982-990 (2010).
Javadi, A., Srithep Y., Pilla, S., Lee, J., Gong, S., and Turng, L. S., Processing and Characterization of Solid and Microcellular PHBV/Coir Fiber Composites, Materials Science and Engineering C-Materials for Biological Applications, 40(5), pp.749-757(2010).
Wang C., Javadi, A., Ghaffari, M., Gong, S., A pH-Sensitive Molecularly Imprinted Nanospheres/Hydrogel Composite as a Coating for Implantable Biosensors, Biomaterials, 31(8), pp. 4944-4951(2010).
Yang, X., Grailer, J. J., Pilla, S., Steeber, D. A., Gong, S., Tumor-targeting, pH-Responsive and Stable Unimolecular Micelles as Drug Nanocarriers for Targeted Cancer Therapy, Bioconjugate Chemistry, 21, pp.496-504(2010).
Yang, M., Li, H., Javadi, A., and Gong, S., Multifunctional Mesoporous Silica Nanoparticles as Labels for the Preparation of Ultrasensitive Electrochemical Immunosensors, Biomaterials, 31, pp.3281-3286(2010)
Javadi, A., Kramschuster A. J., Pilla, S., Lee, J., Gong, S., and Turng, L. S., Processing and Characterization of Microcellular PHBV/PBAT Blends, Polymer Engineering and Science, 50(7), pp.1440-1448 (2010). Highlighted by Society of Plastics Engineers online journal (http://www.4spepro.org/view.php?article=002909-2010-04-07)
Prabaharan, M., Grailer, J. J., Pilla, S., Steeber, D. A., and Gong, S., Gold Nanoparticles with a Monolayer of Doxorubicin-Conjugated Amphiphilic Block Copolymer for Tumor-Targeted Drug Delivery, Biomaterials, 30, pp.6065-6075 (2009).
Prabaharan, M., Grailer, J. J., Pilla, S., Steeber, D. A., and Gong, S., Amphiphilic Multi-Arm-Block Copolymer Conjugated with Doxorubicin via pH-Sensitive Hydrazone Bond for Tumor-Targeted Drug Delivery, Biomaterials, 30, pp.5757-5766 (2009).
Tiwari, A., Grailer, J. J., Pilla, S., Steeber, D. A., and Gong, S., Biodegradable Hydrogels Based on Novel Photopolymerizable Guar Gum-Methacrylate Macromonomers for in situ Fabrication of Tissue Engineering Scaffolds, Acta Biomaterialia,5(9), pp.3441-3452 (2009).
Li, S., and Gong, S, A Substrate-Selective Nanoreactor Made of Molecularly Imprinted Polymer Containing Catalytic Silver Nanoparticles, Advanced Functional Materials, 19(16), pp. 2601-2606 (2009).
Kohlmeyer, R. R., Javadi, A., Pradhan, B., Pilla, S., Setyowati, K., Chen, J., and Gong, S., Electrical and Dielectric Properties of Hydroxylated Carbon Nanotube-Elastomer Composites, Journal of Physical Chemistry, 113(41) pp.17626-17629 (2009).
Li, S. and Gong, S., A Positively Temperature-Responsive, Substrate-Selective Ag Nanoreactor, Journal of Physical Chemistry B, 113 (52), pp. 16501-16507 (2009).
Prabaharan, M., Grailer, J. J., Pilla, S., Steeber, D. A., and Gong, S., Folate-Conjugated Amphiphilic Hyperbranched Copolymers Based on Boltorn H40, Poly(L-lactide) and Poly(ethylene glycol) for Tumor-Targeted Drug Delivery, Biomaterials, 2009, 30: 3009-3019.
Tiwari, A., Aryal, S., Pilla, S., and Gong, S., An Amperometric Urea Biosensor Based on Covalently Immobilized Urease on An Electrode Made of Hyperbranched Polyester Functionalized Gold Nanoparticles, Talanta, 78(4-5), pp. 1401-1407 (2009).
Prabaharan, M., Grailer, J. J., Steeber, D. A., and Gong, S., Thermo-Sensitive Micelles Based on Folate-Conjugated Poly(N-vinylcaprolactam)-block-Poly(ethylene glycol) Copolymers for Tumor-Targeted Drug Delivery, Macromolecule Bioscience, 9(8), pp. 744-753 (2009).
Prabaharan, M., Grailer, J. J., Pilla, S., Steeber, D. A., and Gong, S., Amphiphilic Multi-Arm-Block Copolymer Based on Hyperbranched Polyester, Poly(L-lactide) and Poly(ethylene glycol) as a Drug Delivery Carrier, Macromolecular Bioscience, 9(5), pp. 515-524 (2009).
Pilla, S., Kim, S. G., Auer G. K., Gong, S. and Park, C., Microcellular Extrusion Foaming of Poly(lactide)/Poly(butylene adipate-co-terephthalate) Blends, Materials Science and Engineering C, 30(2), pp. 255-262 (2010). Highlighted by Bioplastics MAGAZINE [01/11] Vol. 6, pp. 36-38.
Pilla, S., Kramschuster, A., Yang, L., Gong, S., Chandra, A., and Turng, L-S., Microcellular Injection-Molding of Polylactide with Chain-Extender, Materials Science and Engineering: C, 29 (4), pp. 1258-1265 (2009).
Pilla, S., Kim, S. G., Auer, G. K., Gong, S., and Park, C. B., Microcellular Extrusion of Polylactide with Chain-Extender, Polymer Engineering and Science, 49(8), pp. 1653-1660 (2009).
Pilla, S., Kramschuster, A., Lee. J., Auer, G.,K, Gong, S., and Turng, L. S., Solid and Microcellular Polylactide-Flax Composites, Composite Interfaces, in press, 2009. Invited contribution.
Aryal, S., Pilla, S., and Gong, S., Multifunctional Nano-micelles Formed by Amphiphilic Gold-Polycaprolactone-Methoxy Poly(ethylene glycol) (Au-PCL-MPEG) Nanoparticles for Potential Drug Delivery Applications, Journal of Nanoscience and Nanotechnology, 9(10), pp.5701-5708 (2009).
Aryal, S., Prabaharan, M., Pilla, S., and Gong, S., Biodegradable and Biocompatible Multi-arm Star Amphiphilic Block Copolymer as a Carrier for Hydrophobic Drug Delivery, International Journal of Biological Macromolecules, 44(4), pp.346-352 (2009).
Li, S., Pilla, S. and Gong, S., Modulated Molecular Recognition by a Temperature-Sensitive Molecularly Imprinted Polymer, Journal of Polymer Science Part A: Polymer Chemistry, 47(9), pp. 2352-2360 (2009).
Yang, L., Setyowati, K., Li, A., Gong, S., and Chen J., Reversible Infrared Actuation of Carbon Nanotube-Liquid Crystalline Elastomer Nanocomposites, Advanced Materials, 20, pp. 2271-2275 (2008).
Prabaharan, M., and Gong, S., Novel Thiolated Carboxymethyl Chitosan-g-beta-cyclodextrin as Mucoadhesive Hydrophobic Drug Delivery Carriers, Carbohydrate Polymers, 73, pp. 117-125 (2008).
Prabaharan, M., Grailer, J. J., Steeber, D. A., and Gong, S., Stimuli-Responsive Chitosan-graft-Poly(N-vinylcaprolactam) as a Promising Material for Controlled Hydrophobic Drug Delivery, Macromolecular Bioscience, 8(9), pp. 843-51 (2008).
Yang, L., Zhang, C., Pilla, S., and Gong, S., Polybenzoxazine-Core Shell Rubber-Carbon Nanotube Nanocomposites, Composites Part A 39, pp. 1653-1659 (2008).

Selected Awards, Honors and Societies

National Science Foundation CAREER Award 2007-2012
University of Wisconsin-Milwaukee Outstanding Research Award 2007
Society for Information Display Award 1998
Pre-doctoral Fellowship University of Michigan-Ann Arbor 1997-1998
Barbour Fellowship University of Michigan-Ann Arbor, 1996-1997
Member of the Editorial Board for the following Journals: Biofabrication; Theranostics; Journal of Biobased Materials and Bioenergy

Summary

Prof. Gong's research group focuses on the design, synthesis/fabrication, and characterization of novel materials and devices. Many of our on-going projects are multidisciplinary, bridging engineering with materials science, chemistry, and the life sciences. Some of our on-going efforts include

1) Multifunctional nanocarriers (e.g., unimolecular micelles, polymer vesicles, functionalized inorganic nanoparticles) for combined delivery of therapeutic and diagnostic agents for targeted cancer therapy and diagnosis

2) Photopolymerizable macromers as tissue engineering scaffolding materials

3) Biosensors (especially electrochemical biosensors) made of nanomaterials for the detection of various biomolecules including antigen, DNA, glucose, and urea

4) Unique hydrogels and hydrogel/nanosphere composites as a coating for implantable biosensors

5) Functional polymer nanocomposites for various types of devices including light and electrical-field stimulated actuators

6) Microcellular injection-molded biobased plastics and composites

Date last modified: 13-Dec-2011
Content by: sgong@engr.wisc.edu
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