Campagnola, Paul J.

S. Plotnikov, V. Juneja, A. Isaacson, W.A. Mohler, and P. J. Campagnola, Optical Clearing for Improved Contrast in Second Harmonic Generation Imaging of Skeletal Muscle, Biophys. J.,90, 328-339 (2006)
S. Plotnikov, A.C. Millard, P.J. Campagnola, and W.A. Mohler, Characterization of the myosin-based source for second-harmonic generation from muscle sarcomeres. Biophys J., 90, 693-703, (2006).
L.P. Cunningham, M.P. Veilleux, and P.J. Campagnola, Freeform multiphoton excited microfabrication for biological applications using a rapid prototyping CAD-based approach, Optics Express, 14, 8613-8621 (2006).
R. LaComb, O. Nadiarnykh, S. Townsend, and P.J. Campagnola, Phase Matching considerations in Second Harmonic Generation from tissues: Effects on emission directionality, conversion efficiency and observed morphology, Optics Comm, 281, 1823-1832 (2008).
R. LaComb, O. Nadiarnykh, and P.J. Campagnola, Second Harmonic Generation imaging of osteogenesis imperfecta: experiment and simulation, Biophys. J., 94, 4504-4514 (2008).
R. LaComb, O. Nadiarnykh, S. Carey and P.J. Campagnola, Quantitative SHG imaging and modeling of the optical clearing mechanism in striated muscle and tendon J. Biomed Opt. 13, 021108 (2008).
X. Chen, M.A. Brewer,C. Zou and P.J. Campagnola, Migration and adhesion of ovarian cancer cells on crosslinked laminin fibers nanofabricated by multiphoton excited photochemistry, Integrative Biology, 1, 469-476 (2009).
O. Nadiarnykh and P. J. Campagnola, Retention of polarization signatures in SHG microscopy of scattering tissues through optical clearing, Optics Express, 17, 5794-5806 (2009)

Arrival at UW

The Campagnola lab re-located to the University of Wisconsin, Madison in the summer of 2010.

Summary

Our lab focuses on studying alterations of the extracellular matrix (ECM) in cancer as well as in connective tissue disorders. To this end, we use Second Harmonic Generation imaging microscopy for imaging structural aspects of tissues, where the approaches will ultimately be implemented as clinical diagnostics. We also use 3D nano/microfabrication approaches to create biomimetic models of the ECM to study signaling pathways associated with cancer and also to provide insight into the design of tissue engineering scaffolds.

Date last modified: 19-Aug-2011
Content by: pcampagnola@wisc.edu
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